horizon
2010-08-26, 12:32 AM
بسم الله الرحمن الرحيم
اولا البحث علمى وموثق ومنشور على موقع بوب ميد
والمكتبة الامريكية الوطنية للطب
http://www.ncbi.nlm.nih.gov
الموقع للتأكد من نتيجة البحث
عنوان البحث
Effect of camel urine on the cytological and biochemical changes induced by cyclophosphamide in mice
تأثير بول الأبل فى التغيرات الخلوية والكيميائية الحادثة بتأثير من السيكلوفوسفامايد _ وهو علاج للسرطان _
ملخص البحث
Abstract
Camel urine treatment was found to cause a significant cytotoxic effect in the bone marrow cells of mice. This cytotoxicity at higher doses was comparable with that of standard drug cyclophosphamide (CP). However, unlike CP, the camel urine treatment failed to induce any clastogenicity. The cytotoxicity induced by camel urine treatment was substantiated by the reduction of liver nucleic acids and glutathione levels and increased malondialdehyde (MDA) #######s in the same animals. CP treatment was found to be highly clastogenic, cytotoxic and it reduced the levels of nucleic acids, proteins, glutathione and increased malondialdehyde concentration due to its prooxidant nature. The non-clastogenic nature of camel urine was attributed to the antioxidant and antimutagenic compounds present in camel urine. Pretreatment with camel urine increased the cytotoxicity of CP and intensified the CP induced reduction of liver nucleic acids, glutathione and increased the MDA concentration. The increase of CP induced cytotoxicity appears to be partly due to the additive effect of the two treatments on cellular lipid peroxidation.
ملخص البحث يثبت ان بول الأبل أقل سمية كما ان له تأثير مضاد للتأكسد وللتحو فى الخلايا - يحافظ عليها من التحو - كما يثبت ان له تأثير علاج مع ملاحظ زيادة سمية العلاج فى حالة أستخدام العلاجين معا بول الابل والسيكلوفوسفاميد للأستخدام المتزامن للعلاجين
اولا البحث علمى وموثق ومنشور على موقع بوب ميد
والمكتبة الامريكية الوطنية للطب
http://www.ncbi.nlm.nih.gov
الموقع للتأكد من نتيجة البحث
عنوان البحث
Effect of camel urine on the cytological and biochemical changes induced by cyclophosphamide in mice
تأثير بول الأبل فى التغيرات الخلوية والكيميائية الحادثة بتأثير من السيكلوفوسفامايد _ وهو علاج للسرطان _
ملخص البحث
Abstract
Camel urine treatment was found to cause a significant cytotoxic effect in the bone marrow cells of mice. This cytotoxicity at higher doses was comparable with that of standard drug cyclophosphamide (CP). However, unlike CP, the camel urine treatment failed to induce any clastogenicity. The cytotoxicity induced by camel urine treatment was substantiated by the reduction of liver nucleic acids and glutathione levels and increased malondialdehyde (MDA) #######s in the same animals. CP treatment was found to be highly clastogenic, cytotoxic and it reduced the levels of nucleic acids, proteins, glutathione and increased malondialdehyde concentration due to its prooxidant nature. The non-clastogenic nature of camel urine was attributed to the antioxidant and antimutagenic compounds present in camel urine. Pretreatment with camel urine increased the cytotoxicity of CP and intensified the CP induced reduction of liver nucleic acids, glutathione and increased the MDA concentration. The increase of CP induced cytotoxicity appears to be partly due to the additive effect of the two treatments on cellular lipid peroxidation.
ملخص البحث يثبت ان بول الأبل أقل سمية كما ان له تأثير مضاد للتأكسد وللتحو فى الخلايا - يحافظ عليها من التحو - كما يثبت ان له تأثير علاج مع ملاحظ زيادة سمية العلاج فى حالة أستخدام العلاجين معا بول الابل والسيكلوفوسفاميد للأستخدام المتزامن للعلاجين